Publications

MDX-1097 induces antibody-dependent cellular cytotoxicity against kappa multiple myeloma cells and its activity is augmented by lenalidomide

Parisa Asvadi, Andrew Cuddihy, Rosanne D. Dunn, Vivien Jiang, Mae X. Wong, Darren R. Jones, Tiffany Khong and Andrew Spencer Link to: Asvadi et al, 2015 BJH)
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Phase 2a, Open-Label, Multi-Dose Study Of Anti-Kappa Monoclonal Antibody, MDX-1097, In Relapsed Kappa-Chain Restricted Multiple Myeloma With Stable Measurable Disease

Rosanne Dunn, Andrew Spencer, Bradley Augustson, Peter Mollee, Michael Copeman and Parisa Asvadi (2013)
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A Phase I study of the anti-kappa monoclonal antibody, MDX-1097, in previously treated multiple myeloma patients

Andrew Spencer, Patricia Walker, Parisa Asvadi, Mae Wong, Douglas Campbell, Kate Reed, Michael Copeman, Geoffrey Nichol, Lewis Cohen and Rosanne Dunn (2010)
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Characterization of a unique conformational epitope on free immunoglobulin kappa light chains that is recognized by an antibody with therapeutic potential

Andrew T. Hutchinson, Ralitza Alexova, Vanessa Bockhornia, Paul A. Ramsland, Darren R. Jones, Cameron V. Jennings, Kevin Broady, Allen B. Edmundson, Robert L. Raison (2011)
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Free Ig Light Chains Interact with Sphingomyelin and Are Found on the Surface of MyelomaPlasma Cells in an Aggregated Form

Andrew T. Hutchinson, Paul A. Ramsland, Darren R. Jones, Mark Agostino, Maria E. Lund, Cameron V. Jennings, Vanessa Bockhorni, Elizabeth Yuriev, Allen B. Edmundson and Robert L. Raison. (2010)
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MDX-1097 Binds Kappa Myeloma Cells Specifically and Its Anti-tumour Activity is Mediated by Multiple Effector Cells

Wong, M., Asvadi, P., Dunn, R., Jones, D., Campbell, D., Spencer, A. (2009)
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Expression of the Kappa Myeloma Antigen on the cell surface of bone marrow aspirates from Waldenstrom's patients

D.R. Jones, P. Asvadi, R.L. Raison, A.T. Hutchinson, A. Spencer, R.D. Dunn (2007)
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A tumor-associated antigen specific for human Kappa Myeloma cells

HA Boux, RL Raison, KZ Walker, GE Hayden and A Basten. (2006)
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A Chimeric Monoclonal Antibody Specific for Kappa Multiple Myeloma Plasma Cells Mediates ADCC of Tumor Cells

R L Raison, D R Jones, P Asvadi, A B H Choo, A T Hutchinson, M J Raison and R D Dunn. (2005)
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A Monoclonal Antibody Specific for Free Human Kappa Light Chains Induces Apoptosis of Multiple Myloma Cells and Exhibits Anti-Tumor Activity in vivo

Paisa Asvadi, Darren R Jones, Rosanne Dunn, Andre BH Choo, Mathew J Raison and Robert L Raison. (2004)
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Antigen binding and cytotoxic properties of a recombinant immunotoxin incorporating the lytic peptide, melittin

Rosanne D. Dunn, Kathryn M. Weston, Terrence J. Longhurst, Glenn G. Lilley, Donald E. Rivett, Peter J. Hudson, Robert L. Raison (1996)
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Structural Analysis of the Myeloma-associated Membrane Antigen KMA

Goodnow, C. C., Raison, R. L., (1985),
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A Monoclonal Antibody with selectivity for Human Kappa Myeloma and Lymphoma cells which has potential as a therapeutic agent

Walker, K. Z., Boux, H.A., Hayden, G.E., Goodnow, C.C., Raison, R.L. (1985)
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Conformation Dependence of a Monoclonal Antibody Defined Epitope on Free Human Kappa Chains

Robert L. Raison and Heather A Boux. (1985)
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Co -expression Of An Epitope On Human Free k light Chains And On A Cytoplasmic Component In Activated T Cells

Karen Walker, Georgina E. Hayden. Christopher C. Goodnow, Heather A. Boux. Elizabeth Adams, Antony Basten, And Robert L. Raison. (1985)
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The surface expression of a tumor associated antigen on human kappa myeloma cells

Robert L. Raison and Heather A Boux, Karen Z Walker, Elizabeth Musgrove and Antony Basten (1983)
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